Showing 20 articles starting at article 361
< Previous 20 articles Next 20 articles >
Categories: Chemistry: Biochemistry, Geoscience: Landslides
Published Robotic nerve 'cuffs' could help treat a range of neurological conditions
(via sciencedaily.com) Original source Researchers have developed tiny, flexible devices that can wrap around individual nerve fibers without damaging them. The researchers combined flexible electronics and soft robotics techniques to develop the devices, which could be used for the diagnosis and treatment of a range of disorders, including epilepsy and chronic pain, or the control of prosthetic limbs.
Published A shortcut for drug discovery
(via sciencedaily.com) Original source For most human proteins, there are no small molecules known to bind them chemically (so called 'ligands'). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines. Researchers at CeMM, in a collaboration with Pfizer, have now leveraged and scaled a method to measure the binding activity of hundreds of small molecules against thousands of human proteins. This large-scale study revealed tens of thousands of ligand-protein interactions that can now be explored for the development of chemical tools and therapeutics. Moreover, powered by machine learning and artificial intelligence, it allows unbiased predictions of how small molecules interact with all proteins present in living human cells. These groundbreaking results have been published in the journal Science (DOI: 10.1126/science.adk5864), and all generated data and models are freely available for the scientific community.
Published Estimating emissions potential of decommissioned gas wells from shale samples
(via sciencedaily.com) Original source Extracting natural gas from shale formations can provide an abundant, lower-carbon footprint fossil fuel, but also creates concerns over increased methane emissions. Researchers have now developed a new tool that can estimate the emission potential of shale wells after they are no longer active.
Published Nanomaterial that mimics proteins could be basis for new neurodegenerative disease treatments
(via sciencedaily.com) Original source A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases. The nanomaterial alters the interaction between two key proteins in brain cells -- with a potentially powerful therapeutic effect.
Published 'Like a nanoscopic Moon lander': Scientists unlock secret of how pyramidal molecules move across surfaces
(via sciencedaily.com) Original source Scientists have watched a molecule move across a graphite surface in unprecedented detail. It turns out this particular molecule moves like a Moon lander -- and the insights hold potential for future nanotechnologies.
Published Towards novel promising perovskite-type ferroelectric materials: High-pressure synthesis of rubidium niobate
(via sciencedaily.com) Original source Researchers have pioneered a breakthrough in ferroelectric material development. They've engineered a novel displacement-type ferroelectric material boasting remarkable dielectric properties. Their achievement includes the successful synthesis of rubidium niobate (RbNbO3), a compound previously deemed challenging to produce under pressures exceeding 40,000 atmospheres. Additionally, they characterized how polarization changes across a wide temperature range during phase transitions. This breakthrough can lead to new design guidelines for ferroelectric materials.
Published The secret to saving old books could be gluten-free glues
(via sciencedaily.com) Original source 'Bookworm' is a cute thing to call a voracious reader, but actual bookworms -- as well as microorganisms and time -- break down the flour pastes commonly used to keep old publications in one piece. Now, researchers have analyzed the proteins in wheat-based glues applied in historic bookbinding to provide insights on their adhesiveness and how they degrade. This information could help conservators restore and preserve treasured tomes for future generations.
Published Why can't robots outrun animals?
(via sciencedaily.com) Original source Robotics engineers have worked for decades and invested many millions of research dollars in attempts to create a robot that can walk or run as well as an animal. And yet, it remains the case that many animals are capable of feats that would be impossible for robots that exist today.
Published Pattern formation in the nano-cosmos
(via sciencedaily.com) Original source A new model extends the theory of elastic phase separation towards nanoscopic structures. Such patterns are frequent in biological systems and also used in nano-engineering to create structural color. With their new insights, the scientists can predict the length scale of nanoscopic patterns and thus control them during production.
Published Biophysics: Testing how well biomarkers work
(via sciencedaily.com) Original source Researchers have developed a method to determine how reliably target proteins can be labeled using super-resolution fluorescence microscopy.
Published A chemical mystery solved -- the reaction explaining large carbon sinks
(via sciencedaily.com) Original source A mystery that has puzzled the scientific community for over 50 years has finally been solved. A team has discovered that a certain type of chemical reaction can explain why organic matter found in rivers and lakes is so resistant to degradation.
Published Condensed matter physics: Novel one-dimensional superconductor
(via sciencedaily.com) Original source In a significant development in the field of superconductivity, researchers have successfully achieved robust superconductivity in high magnetic fields using a newly created one-dimensional (1D) system. This breakthrough offers a promising pathway to achieving superconductivity in the quantum Hall regime, a longstanding challenge in condensed matter physics.
Published Lead-vacancy centers in diamond as building blocks for large-scale quantum networks
(via sciencedaily.com) Original source A lead-vacancy (PbV) center in diamond has been developed as a quantum emitter for large-scale quantum networks by researchers. This innovative color center exhibits a sharp zero-phonon-line and emits photons with specific frequencies. The PbV color center stands out among other diamond color centers due to its ability to maintain optical properties at relatively high temperatures of 16 K. This makes it well-suited for transferring quantum information in large-scale quantum networks.
Published Critical minerals recovery from electronic waste
(via sciencedaily.com) Original source A nontoxic separation process recovers critical minerals from electronic scrap waste.
Published Researchers create artificial cells that act like living cells
(via sciencedaily.com) Original source Researchers describe the steps they took to manipulate DNA and proteins -- essential building blocks of life -- to create cells that look and act like cells from the body. This accomplishment, a first in the field, has implications for efforts in regenerative medicine, drug delivery systems and diagnostic tools.
Published Gentle defibrillation for the heart
(via sciencedaily.com) Original source Using light pulses as a model for electrical defibrillation, scientists developed a method to assess and modulate the heart function. The research team has thus paved the way for an efficient and direct treatment for cardiac arrhythmias. This may be an alternative for the strong and painful electrical shocks currently used.
Published AI tool creates 'synthetic' images of cells for enhanced microscopy analysis
(via sciencedaily.com) Original source Researchers have developed a method to use an image generation AI model to create realistic images of single cells, which are then used as 'synthetic data' to train an AI model to better carry out single-cell segmentation.
Published This alloy is kinky
(via sciencedaily.com) Original source Researchers have uncovered a remarkable metal alloy that won t crack at extreme temperatures due to kinking, or bending, of crystals in the alloy at the atomic level. Unlike most materials, the new alloy keeps its shape and resists cracking at both high and low temperature extremes, making it potentially suitable for demanding applications like high-efficiency aerospace engines.
Published Switching off the light to see better
(via sciencedaily.com) Original source Researchers used structured light and switchable fluorescent molecules to reduce the background light from the out-of-plane regions of microscope samples. This method allowed for the acquisition of images that surpassed the conventional resolution limit, and it may be useful for further study of cell clusters and other biological systems.
Published New copper-catalyzed C-H activation strategy
(via sciencedaily.com) Original source Inspired by what human liver enzymes can do, chemists have developed a new set of copper-catalyzed organic synthesis reactions for building and modifying pharmaceuticals and other molecules. The new reactions are expected to be widely used in drug discovery and optimization, as well as in other chemistry-based industries.