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Categories: Chemistry: Biochemistry, Geoscience: Environmental Issues
Published Electrical impedance tomography--extracellular voltage activation technique simplifies drug screening
(via sciencedaily.com) Original source Recently, researchers developed a non-invasive method combining electrical impedance tomography and extracellular voltage activation to evaluate drug effects on ion channels. The resulting printed circuit board sensor allows real-time monitoring of how newly developed drugs can affect ion flow in channels, providing a cost-effective and accurate alternative to traditional methods like patch-clamp techniques and paving the way toward more efficient and shorter preclinical testing in the drug discovery process.
Published Proteins as the key to precision medicine: Finding unknown effects of existing drugs
(via sciencedaily.com) Original source Fewer side effects, improved chances of healing: the goal of precision medicine is to provide patients with the most individualized treatment possible. This requires a precise understanding of what is happening at the cellular level. Researchers have now succeeded in mapping the interactions of 144 active substances with around 8,000 proteins. The results could help to identify previously unknown potential benefits of existing drugs.
Published Warming stops tiny organisms working together
(via sciencedaily.com) Original source Hotter conditions prevent two tiny organisms working together for mutual benefit, new research shows.
Published Tipping risks from overshooting 1.5 °C can be minimized if warming is swiftly reversed
(via sciencedaily.com) Original source Current climate policies imply a high risk for tipping of critical Earth system elements, even if temperatures return to below 1.5 C of global warming after a period of overshoot. A new study indicates that this risk can be minimized if the warming is swiftly reversed. That is why reducing emissions in the current decade is crucial for the stability of the Earth systems functions, researchers write. They analyzed the tipping risks for four interconnected core climate tipping elements: the Greenland Ice Sheet, the West Antarctic Ice Sheet, the Atlantic Meridional Overturning Circulation (AMOC), and the Amazon Rainforest.
Published Towards smart cities: Predicting soil liquefaction risk using artificial intelligence
(via sciencedaily.com) Original source Soil liquefaction that results in infrastructure damage has long been a point of contention for urban planners and engineers. Accurately predicting the soil liquefaction risk of a region could help overcome this challenge. Accordingly, researchers applied artificial intelligence to generate soil liquefaction risk maps, superseding already published risk maps.
Published The next generation of RNA chips
(via sciencedaily.com) Original source An international research team has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient.
Published 3D models provide unprecedented look at corals' response to bleaching events
(via sciencedaily.com) Original source Marine biologists are providing a glimpse into coral 'bleaching' responses to stress, using imaging technology to pinpoint coral survival rates following multiple bleaching events off the island of Maui. Using a time series of coral reef 3D models from Maui, the researchers tracked the bleaching response of 1,832 coral colonies from 2014 to 2021. The seven-year data set provided detailed imagery of the reefs year-by-year, allowing the team to identify patterns of coral growth and survivorship through sequential bleaching events that occurred in 2015 and 2019.
Published Underwater mapping reveals new insights into melting of Antarctica's ice shelves
(via sciencedaily.com) Original source Clues to future sea level rise have been revealed by the first detailed maps of the underside of a floating ice shelf in Antarctica. An international research team deployed an unmanned submersible beneath the Dotson Ice Shelf in West Antarctica.
Published Downwind states face disproportionate burden of air pollution
(via sciencedaily.com) Original source A recent U.S. Supreme Court decision to block a federal rule curbing interstate air pollution further complicates efforts to reduce emissions and adds to an already disproportionate burden on 'downwind' states, according to researchers.
Published Smell reports reveal the need to expand urban air quality monitoring, say researchers
(via sciencedaily.com) Original source Researchers have uncovered surprising insights into the Vancouver region's 'smellscape' using data from the Smell Vancouver app. Analyzing 549 reports from one year of app data, they discovered that 'rotten' and 'chemical' odours dominated, making up about 65 per cent of submissions. These unpleasant smells were linked to self-reported health issues like headaches and anxiety, leading some residents to change their behaviours, like closing windows even in stifling-hot weather.
Published Scientists devise method to secure Earth's biodiversity on the moon
(via sciencedaily.com) Original source New research led proposes a plan to safeguard Earth's imperiled biodiversity by cryogenically preserving biological material on the moon. The moon's permanently shadowed craters are cold enough for cryogenic preservation without the need for electricity or liquid nitrogen.
Published Climate change means that tropical cyclones in Southeast Asia are developing faster, lasting longer
(via sciencedaily.com) Original source A study reveals that tropical cyclones in Southeast Asia are now forming closer to coastlines, intensifying more rapidly, and lingering longer over land.
Published What's the weather like in the deep sea?
(via sciencedaily.com) Original source A new study has revealed how even the deepest seafloors are affected by the daily back-and-forth of the tides, and the change of the seasons, and that currents at the bottom of the ocean are far more complicated than previously thought. These findings are helping us understand the deep-sea pathways of nutrients that support important deep-sea ecosystems, assess where microplastics and other pollutants accumulate in the ocean, and reconstruct past climate change.
Published Researchers explore the potential of clean energy markets as a hedging tool
(via sciencedaily.com) Original source Clean energy investments offer potential stability and growth, especially during volatile market conditions. A recent study explored the relationship between clean energy markets and global stock markets. Significant spillovers were observed from major indices like the SP500 to markets such as Japan's Nikkei225 and Global Clean Energy Index. These interactions suggest opportunities for optimizing investment portfolios and leveraging clean energy assets as hedging tools in volatile market environments.
Published Improving Alzheimer's disease imaging -- with fluorescent sensors
(via sciencedaily.com) Original source Neurotransmitter levels in the brain can indicate brain health and neurodegenerative diseases like Alzheimer's. However, the protective blood-brain barrier (BBB) makes delivering fluorescent sensors that can detect these small molecules to the brain difficult. Now, researchers demonstrate a way of packaging these sensors for easy passage across the BBB in mice, allowing for improved brain imaging. With further development, the technology could help advance Alzheimer's disease diagnosis and treatment.
Published More electricity from the sun
(via sciencedaily.com) Original source A coating of solar cells with special organic molecules could pave the way for a new generation of solar panels. This coating can increase the efficiency of monolithic tandem cells made of silicon and perovskite while lowering their cost -- because they are produced from industrial, microstructured, standard silicon wafers.
Published Physicists use light to probe deeper into the 'invisible' energy states of molecules
(via sciencedaily.com) Original source Physicists have experimentally demonstrates a novel physical effect that was predicted 45 years ago. The effect will result in a new chemical analysis technique, to simultaneously identify molecular bonds and their 3D arrangement in space. This new technique will find applications in pharmaceutical science, security, forensics, environmental science, art conservation, and medicine.
Published Unraveling a key junction underlying muscle contraction
(via sciencedaily.com) Original source Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal kingdom and setting the stage for possible future treatments for muscular disorders.
Published Genes or environment? A new model for understanding disease risk factors
(via sciencedaily.com) Original source Researchers have developed a model that more accurately predicts how genetics and air pollution levels causally influence disease development.
Published Super-black wood can improve telescopes, optical devices and consumer goods
(via sciencedaily.com) Original source Thanks to an accidental discovery, researchers have created a new super-black material that absorbs almost all light, opening potential applications in fine jewelry, solar cells and precision optical devices.