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Categories: Chemistry: Biochemistry, Paleontology: Early Mammals and Birds

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Protein cages found in nature within microbes help weather its contents from the harsh intracellular environment -- an observation with many bioengineering applications. Researchers recently developed an innovative bioengineering approach using genetically modified bacteria; these bacteria can incorporate protein cages around protein crystals. This in-cell biosynthesis method efficiently produces highly customized protein complexes, which could find applications as advanced solid catalysts and functionalized nanomaterials.

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Planetary rovers, which help humanity explore other planets, can deviate from their targeted paths or get stuck due to slipping on loose soil. To combat this problem, researchers have developed a novel system for rovers to detect their slip condition from the change in the shape of their chassis. This novel technology, inspired by human muscles, can lead to advanced sensing technologies that make travel safer for unmanned vehicles.

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A research team has now directly measured the so-called Kondo effect, which governs the behavior of magnetic atoms surrounded by a sea of electrons: New observations with a scanning tunneling microscope reveal the effect in one-dimensional wires floating on graphene. 

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Recently, morning omelets and holiday dinners have gotten more expensive. One likely cause is bird flu, outbreaks of which led to the deaths of millions of chickens and turkeys from infection or culling in 2022, according to the U.S. Department of Agriculture, and which still demands rigorous monitoring of wild populations. Now, researchers have developed a method that detected infectious bird flu virus in wetlands frequented by waterfowl.

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Scientists have 3D-printed hair follicles in human skin tissue cultured in the lab. This marks the first time researchers have used the technology to generate hair follicles, which play an important role in skin healing and function. When it comes to engineering human skin, hair may at first seem superfluous. However, hair follicles are quite important: They produce sweat, helping regulate body temperature, and they contain stem cells that help skin heal. The finding has potential applications in regenerative medicine and drug testing, though engineering skin grafts that grow hair are still several years away.  

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Researchers have developed a more efficient way to find out which new 'designer drugs' are circulating in the community. In a new study, they showed how high-resolution mass spectrometry can be used to analyze urine samples at scale and uncover molecules from emerging designer drugs that have been missed by conventional testing. The approach can support public health and safety by enabling swift identification of new substances, potentially saving lives and guiding timely clinical responses to drug-related emergencies.

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Engineers have developed a high-throughput, multimaterial 3D inkjet printer that uses computer vision to rapidly and automatically control the amount of material being deposited during the printing process in real time. This enables the use of a wide range of materials for fabrication.

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Researchers have designed micromotors that move around on their own to purify wastewater. The process creates ammonia, which can serve as a green energy source. Now, an AI method will be used to tune the motors to achieve the best possible results.

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Absorbing excess sound to make public environments like theaters and concert halls safer for hearing and using the unwanted sound waves to create electricity is the aim of a new paper. The authors built a system of piezoelectric sensors that can be installed in walls, floors, and ceilings to absorb sound waves and collect their energy. They used computer simulations to fine-tune variables including the voltage needed to power the main device component, the frequency and intensity of the input sound, and piezoelectric sensors tested in parallel and serial configurations.

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Far from being stiff and pointy, a coronavirus's infectious spikes are shaped like chicken drumsticks with the meaty part facing out, and the meaty part can tilt every which way on its slender stalk. A new study suggests that disabling those hinges could block infection.

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An international team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer's and Parkinson's Diseases. The biosensor can also transmit the results wirelessly to a laptop or smartphone. The team tested the device on in vitro samples from patients and showed that it is as accurate as the state of the art method. Ultimately, researchers plan to test saliva and urine samples with the biosensor. The device could be modified to detect biomarkers for other conditions as well. The device relies on electrical rather than chemical detection, which researchers say is easier to implement and more accurate.   

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Researchers have identified the potential environmental risks of using ammonia as a zero-carbon fuel in order to develop an engineering roadmap to a sustainable ammonia economy.

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Artificial intelligence (AI) is on the rise. Until now, AI applications generally have 'black box' character: How AI arrives at its results remains hidden. A cheminformatics scientist has now developed a method that reveals how certain AI applications work in pharmaceutical research. The results are unexpected: the AI programs largely remembered known data and hardly learned specific chemical interactions when predicting drug potency.

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A research team has developed a reversible, water-based glue that has good adhesion in the neutral pH range, but can be detached again in strongly acidic or alkaline environments. The novel adhesive system, which is based on electrostatic interactions, has bond strengths somewhere between those of structural adhesives and pressure-sensitive adhesives. The new adhesive also bonds 'difficult' surfaces such as water-repellent polypropylene.

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Deep within every piece of magnetic material, electrons dance to the invisible tune of quantum mechanics. Their spins, akin to tiny atomic tops, dictate the magnetic behavior of the material they inhabit. This microscopic ballet is the cornerstone of magnetic phenomena, and it's these spins that a team of researchers has learned to control with remarkable precision, potentially redefining the future of electronics and data storage.

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New research provides a deeper understanding of the way components within cells are interconnected. Through cellular visualization using SRS microscopy, researchers have addressed the challenge of attaining clear images of individual processes.

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Scientists demonstrate a novel approach for creating high-performance ultrafast lasers on nanophotonic chips. The new advance will enable pocket-sized devices that can perform detailed GPS-free precision navigation, medical imaging, food safety inspection and more.  

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Researchers have developed a new method to image polymerization catalysis reactions one monomer at a time. 

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Researchers have developed a new way of counting microorganisms that works as much as 36 times faster than conventional methods, cuts plastic use more than 15-fold and substantially decreases the cost and carbon footprint of biomedical research. The technique could revolutionize the way microbiology experiments are conducted, allowing researchers to test potential new antibiotics in a fraction of the time.

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Scientists used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.