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Categories: Chemistry: Biochemistry, Offbeat: Plants and Animals

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The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.

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While there's no regulation in the U.S. for what's in organic shampoos, they tend to contain ingredients perceived as safe or environmentally friendly. However, these 'clean' shampoos separate and spoil faster than those made with synthetic stabilizers and preservatives. Now, researchers demonstrate that a simple process -- spinning organic shampoo at high speeds -- improved the final products' shelf lives and ability to clean hair.

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Tyche is a machine-learning framework that can generate plausible answers when asked to identify potential disease in medical images. By capturing the ambiguity in images, the technique could prevent clinicians from missing crucial information that could inform diagnoses.

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Researchers show that ozone levels, such as those found in many places on hot summer days today, destroy the sex pheromones of fruit fly species. As a result, some natural mating boundaries maintained by species-specific pheromones no longer exist. The research team has shown in experiments that flies of different species mate when exposed to ozone and produce hybrid offspring. Since most of these offspring are unable to reproduce, the results could provide another explanation for the global decline of insects.

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Cloud 'engineering' could be more effective for climate cooling than previously thought, because of the increased cloud cover produced, new research shows.

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Researchers have developed synthetic platelets that can be used to stop bleeding and enhance healing at the site of an injury. The researchers have demonstrated that the synthetic platelets work well in animal models but have not yet begun clinical trials in humans.

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Researchers have developed a novel method of adding polyethylene glycol molecules to engineered groups of messenger RNAs called 'mRNA polyplexes', which enable the cells that receive them to produce specific proteins. This technique allows greater control of the site in the body to which the polyplexes are delivered, significantly advancing the field of therapeutic mRNA technologies, with applications in vaccine development and the treatment of cancer and other diseases.

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Chemists show that a machine-based method prevents widespread 'bias' in chemical publications.

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In a new breakthrough that could revolutionise medical and material engineering, scientists have developed a first-of-its-kind molecular device that controls the release of multiple small molecules using force.

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Wirelessly connected devices perform an expanding array of applications, such as monitoring the condition of machinery and remote sensing in agricultural settings. These applications hold much potential for improving the efficiency, but how do you power these devices where reliable electrical sources are not available? Research points to a possible solution in the form of a novel type of battery.

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Scientists from Macquarie University have come up with an innovative way to stop cane toads killing native wildlife by training goannas to avoid eating the deadly amphibians.

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A study that could help revolutionize wireless communication introduces a novel method to curve terahertz signals around an obstacle.

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Scientists are using computer simulations and laboratory experiments to see if depleted oil and natural gas reservoirs can be used for storing carbon-free hydrogen fuel. Hydrogen is an important clean fuel: It can be made by splitting water using solar or wind power, it can be used to generate electricity and power heavy industry, and it could be used to power fuel-cell-based vehicles. Additionally, hydrogen could be stored for months and used when energy needs outpace the supply delivered by renewable energy sources.

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Several similar large, fossilized bone fragments have been discovered in various regions across Western and Central Europe since the 19th century. The animal group to which they belonged is still the subject of much debate to this day. A study could now settle this dispute once and for all: The microstructure of the fossils indicates that they come from the lower jaw of a gigantic ichthyosaur. These animals could reach 25 to 30 meters in length, a similar size to the modern blue whale.

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Researchers unveiled BeatProfiler, a groundbreaking new tool -- a comprehensive software that automates the analysis of heart cell function from video data. It's the first system to integrate the analysis of different heart function indicators, such as contractility, calcium handling, and force output into one tool, speeding up the process significantly and reducing the chance for errors. BeatProfiler enabled the researchers to not only distinguish between different diseases and levels of their severity but also to rapidly and objectively test drugs that affect heart function.

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Genetic analysis finds evidence suggesting that acoustic fat bodies in the heads of toothed whales were once the muscles and bone marrow of the jaw.

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A new molecular test method helps to prove the authenticity of works of art. The new method could also help to make passwords secure against quantum computers.

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Did you know that the world's deadliest animal is the mosquito? And Aedes aegypti is one of the most dangerous. This bug spreads viruses that cause dengue fever, which was recently declared as an epidemic in Puerto Rico. Research reports new molecules that label proteins in the unique, alkaline environment of the Ae. aegypti digestive system that could help scientists develop insecticides to fight back.

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Scientists are amazed at the discovery of a bristle worm with such sharp-seeing eyes that they can measure up to those of mammals and octopuses. The researchers suspect that these marine worms may have a secretive language, which uses UV light only seen by their own species. The advanced vision of such a primitive creature helps to finally settle an epic debate about the evolution of eyes.

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Scientists have developed an automated workflow that could accelerate the discovery of new pharmaceutical drugs and other useful products. The new automated approach could analyze chemical reactions in real time and identify new chemical-reaction products much faster than current laboratory methods.