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Categories: Chemistry: Biochemistry, Offbeat: Earth and Climate
Published Where to put head and tail?



Formation of the body axes is a critical part of embryonic development. They guarantee that all body parts end up where they belong and that no ears grow on our backs. The head-tail axis, for example, determines the orientation of the two ends of the body. It was previously assumed that this axis is largely determined by the interplay between the Nodal and BMP signals. However, there appears to be another player in this system, as researchers have now discovered by using an embryo-like model system they developed. In the absence of BMP, the signalling molecule beta-catenin takes on the role of the Nodal antagonist. This new mechanism could be a flexible solution for axis formation in embryos with different shapes.
Published Custom-made molecules designed to be invisible while absorbing near-infrared light



Researchers used theoretical calculations assessing electron orbital symmetry to synthesize new molecule designed to be both transparent and colorless while absorbing near-infrared light. This compound demonstrates the first systematic approach to producing such materials and have applications in advanced electronics. This compound also shows semiconducting properties.
Published Wear it, then recycle: Designers make dissolvable textiles from gelatin



Researchers hope their DIY machine will help designers around the world experiment with making their own, sustainable fashion and other textiles from a range of natural ingredients -- maybe even the chitin in crab shells or agar-agar from algae.
Published Molecular sponge for the electronics of the future



An international research team has succeeded in developing a new type of material in the rather young research field of covalent organic frameworks. The new two-dimensional polymer is characterized by the fact that its properties can be controlled in a targeted and reversible manner. This has brought the researchers a step closer to the goal of realizing switchable quantum states.
Published Breakthrough approach enables bidirectional BCI functionality



Brain-computer interfaces or BCIs hold immense potential for individuals with a wide range of neurological conditions, but the road to implementation is long and nuanced for both the invasive and noninvasive versions of the technology. Scientists have now successfully integrated a novel focused ultrasound stimulation to realize bidirectional BCI that both encodes and decodes brain waves using machine learning in a study with 25 human subjects. This work opens up a new avenue to significantly enhance not only the signal quality, but also, overall nonivasive BCI performance by stimulating targeted neural circuits.
Published Some CRISPR screens may be missing cancer drug targets



CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow. These genes, or 'cancer dependencies,' are often promising drug targets. But new research shows that many of these CRISPR screening experiments rely on components, called CRISPR/Cas9 guides, that do not perform equally well in cells from people of all ancestries, which can cause CRISPR screens to miss cancer dependencies.
Published When bacteria are buckling



Filamentous cyanobacteria buckle at a certain length when they encounter an obstacle. The results provide an important basis for the use of cyanobacteria in modern biotechnology.
Published Nano-immunotherapy developed to improve lung cancer treatment



Researchers have developed a new nanomedicine therapy that delivers anticancer drugs to lung cancer cells and enhances the immune system's ability to fight cancer. The team showed promising results for the new therapy in cancer cells in the lab and in mouse lung tumor models, with potential applications for improving care and outcomes for patients with tumors that have failed to respond to traditional immunotherapy.
Published Strengthener for graphene



Layers of carbon atoms in a honeycomb array are a true supermaterial: their unusually high conductivity and favorable mechanical properties could further the development of bendable electronics, new batteries, and innovative composite materials for aeronautics and space flight. However, the development of elastic and tough films remains a challenge. A research team has now introduced a method to overcome this hurdle: they linked graphene nanolayers via 'extendable' bridging structures.
Published Self-assembling and disassembling swarm molecular robots via DNA molecular controller



Researchers have succeeded in developing a DNA-based molecular controller. Crucially, this controller enables the autonomous assembly and disassembly of molecular robots, as opposed to manually directing it.
Published Novel insights into fluorescent 'dark states' illuminate ways forward for improved imaging



Scientists address decades-long problem in the field of single-molecule fluorescence resonance energy transfer, paving the way for more accurate experiments.
Published Sweaty cattle may boost food security in a warming world



Climate change is making it more difficult to raise cattle -- growth and reproduction are affected by heat -- so it's critical to breed cattle better adapted to a hotter and longer summer. A new study shows it's possible to identify the genes within breeds of cattle that would lead to the sweatiest, heat-tolerant offspring.
Published Making ferromagnets ready for ultra-fast communication and computation technology



Researchers have made a significant breakthrough in how to enable and exploit ultra-fast spin behavior in ferromagnets. The research paves the way for ultra-high frequency applications.
Published Lab achieves major gains in perovskite solar cell stability



Researchers have developed new chemistry to achieve commercially relevant stability and performance for perovskite solar cells.
Published Scientists preserve DNA in an amber-like polymer



With their 'T-REX' method, researchers developed a glassy, amber-like polymer that can be used for long-term storage of DNA, such as entire human genomes or digital files such as photos.
Published The rotation of Earth's inner core has slowed, new study confirms



The new study provides unambiguous evidence that the inner core began to decrease its speed around 2010, moving slower than the Earth's surface.
Published Technologies enable 3D imaging of whole human brain hemispheres at subcellular resolution



A suite of three innovations enables high-resolution, high-throughput imaging of human brain tissue at a full range of scales and mapping connectivity of neurons at single cell resolution. To demonstrate the advance, researchers compared a brain region in an Alzheimer's and a control sample.
Published Parliamentary members use simpler language on hot days



Climate change has many widespread and complicated effects on the well-being of people and the planet, and a new study has now added a surprising one to the list. After analyzing the language used in seven million parliamentary speeches around the world, it shows that high temperatures lead to a significant and immediate reduction in politicians' language complexity.
Published Swimming microrobots deliver cancer-fighting drugs to metastatic lung tumors in mice



Engineers have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors. This approach has shown promise in mice, where it inhibited the growth and spread of tumors that had metastasized to the lungs, thereby boosting survival rates compared to control treatments.
Published Mobile monitoring for an airborne carcinogen in Louisiana's 'Cancer Alley'



Louisiana's southeastern corridor is sometimes known colloquially as 'Cancer Alley' for its high cancer incidence rates connected to industrial air pollution. Most of the region's air pollution-related health risks are attributed to ethylene oxide, a volatile compound used to make plastics and sterilize medical equipment. Researchers measured concerning levels of ethylene oxide in this area with mobile optical instruments, a technique they say could improve health risk assessments.