Search query: off-target
Categories: All Categories
13142 records searched, 16 records found
Search Hints:
- Use a + (plus sign) or - (minus sign) to include or exclude a word: +mars -venus
- Use a ? (question mark) as a wildcard for a single letter: te?t (test,text)
- Use a * (asterisk) as a wildcard for multiple letters: he*t (heat, heart)
- Use a ~ (tilde) to expand word endings: meteor~ (meteorite, meteorid, meteorology)
Most frequent words for articles published in the last 45 days:
developed (95),
climate (85),
team (83),
species (75),
cells (74),
used (72),
human (64),
help (61),
change (60),
water (60),
years (60),
data (57),
energy (55),
such (53),
carbon (51),
discovered (50),
time (48),
like (47),
materials (46),
even (44)
Published Genome editing: Reducing off-target mutations in DNA - Genome Editing: A Leap Forward in Reducing Off-Target Mutations in DNA
(via sciencedaily.com) Original source Researchers have developed a novel genome editing technique known as NICER, which results in signifi...
Published Weaker transcription factors are better when they work together
(via sciencedaily.com) Bioengineers have developed a generalizable method to address 'off-target' binding, a significant pr ...
Published Safer CRISPR gene editing with fewer off-target hits - Safer CRISPR Gene Editing with Fewer Off-Target Hits
(via sciencedaily.com) The CRISPR system is a powerful tool for the targeted editing of genomes, with significant therapeut...
Published Modified CRISPR-based enzymes improve the prospect of inserting entire genes into the genome to overcome diverse disease-causing mutations - Modified CRISPR-based Enzymes: A Promising Solution to Overcome Disease-Causing Mutations
(via sciencedaily.com) Original source Many genetic diseases are caused by diverse mutations spread across an entire gene, and designing ge...
Published Accurate evaluation of CRISPR genome editing - Accurate Evaluation of CRISPR Genome Editing
(via sciencedaily.com) Researchers have developed a new software tool to detect, evaluate and quantify off-target editing a ...
Published New nanoparticles can perform gene-editing in the lungs - New Nanoparticles Can Perform Gene-Editing in the Lungs
(via sciencedaily.com) Original source A new type of nanoparticle can be administered to the lungs, where it can deliver messenger RNA enco...
Published Researchers develop DANGER analysis tool for the safer design of gene editing
(via sciencedaily.com) Original source A team of researchers has developed a software tool that provides a way for the safer design of geno...
Published The achilles heel of the influenza virus: Ubiquitin protein may be an approach for future medicines - The Achilles Heel of the Influenza Virus: Ubiquitin Protein May Be an Approach for Future Medicines
(via sciencedaily.com) Original source Influenza viruses are becoming increasingly resilient to medicines. For this reason, new active ingr...
Published Scientists create CRISPR-based drug candidate targeting the microbiome - Scientists Create CRISPR-Based Drug Candidate Targeting the Microbiome
(via sciencedaily.com) Original source A new drug candidate targeting E. coli in the gut is in phase 1 clinical trials. According to a new...
Published Novel nanocages for delivery of small interfering RNAs - Novel Nanocages for Delivery of Small Interfering RNAs
(via sciencedaily.com) Original source Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of dis...
Published Fluorine-based new drug synthesis at lightning speed - Fluorine-Based New Drug Synthesis at Lightning Speed
(via sciencedaily.com) Original source Researchers synthesize fluorine-based compound via rapid biphasic (gas and liquid) mixing. ABSTRACT:...
Published Scientists develop gene silencing DNA enzyme that can target a single molecule - Scientists Develop Gene Silencing DNA Enzyme That Can Target a Single Molecule
(via sciencedaily.com) Original source Researchers have developed a DNA enzyme -- or DNAzyme -- that can distinguish between two RNA strand...
Published Scientists use DNA origami to monitor CRISPR gene targeting - Scientists Use DNA Origami to Monitor CRISPR Gene Targeting
(via sciencedaily.com) The remarkable genetic scissors called CRISPR/Cas9, the discovery that won the 2020 Nobel Prize in C...
Published Keeping SARS-CoV-2 closed for business with small molecules - Keeping SARS-CoV-2 Closed for Business with Small Molecules
(via sciencedaily.com) The infamous spike proteins on the surface of SARS-CoV-2 help it bind to and enter human cells. Beca...
Published Genome editing used to create disease resistant rice - Genome Editing Used to Create Disease Resistant Rice
(via sciencedaily.com) Original source Researchers have used the genome-editing tool CRISPR-Cas to create disease resistant rice plants, ac...
Published New trick up their sleeve - New Trick Up Their Sleeve: How Scientists are Using Nanoparticles to Fight Cancer
(via sciencedaily.com) Nerve-damaging protein particles called prions have long been known to exist in mammals. Now, in a s...