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Categories: Archaeology: General, Biology: Molecular

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A newly published study of a stalagmite found in Cave of the Mounds reveals previously undetected history of the local climate going back thousands of years. Researchers describe evidence for an ice age punctuated by massive and abrupt warming events across much of the Northern Hemisphere.

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In early cytological studies chromatids of metaphase chromosomes were suggested to coil into a spiral called chromonema. This assumption was recently supported by chromosomce conformation capture sequencing. Still, the direct visualization of the coiled chromonema confirming the helical model was lacking. Now, an international research team provides the direct proof of the helical coiling of condensed chromatids via super-resolution microscopy of specifically labelled chromonema regions.

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A large Bronze Age debris deposit in Mycenae, Greece provides important data for understanding the history of animal resources at the site, according to a new study.

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A world-first model of paleoclimate and hydrology in Iran has highlighted favourable routes for Neanderthals and modern human expansions eastwards into Asia. The findings reveal that multiple humid periods in ancient Iran led to the expansions of human populations, opening dispersal route across the region, and the possible interactions of species such as Neanderthals and our own Homo sapiens.

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Scientists recently developed an efficient way to transplant pancreatic islets and demonstrated that the method can effectively reverse type 1 diabetes in nonhuman primates.

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A new study reports on genomic data from a 23,000-year-old individual who lived in what was probably the warmest place of Europe at the peak of the last Ice Age. The oldest human genome recovered from the southern tip of Spain adds an important piece of the puzzle to the genetic history of Europe.

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A major new study reveals a 'traffic light' mechanism controlling genetic activity within cells -- a system which could potentially be targeted by cancer drugs already in development. The research describes how 'epigenetic' changes to the structure of DNA can act as a stop-go signal in determining whether a gene should be read. Unlike our genetic make-up, which is well understood, the world of epigenetics is still largely unexplored and referred to as the 'dark matter' of the genome.

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A detailed atlas of gene expression in the zebrafish brain.

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Researchers have discovered what they believe is the earliest use of steel in Europe -- on Iberian stone pillars from the Final Bronze Age.

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In 2011, scientists recorded a previously unknown feeding strategy in whales around the world. Now, researchers in Australia think they may have found evidence of this behaviour being described in ancient accounts of sea creatures, recorded more than 2,000 years ago. They believe that misunderstandings of these descriptions contributed to myths about medieval sea monsters. Whales are known lunge at their prey when feeding, but recently whales have been spotted at the surface of the water with their jaws open at right angles, waiting for shoals of fish to swim into their mouths. A clip of this strategy was captured in 2021 and went viral on Instagram. This strategy seems to work for the whales because the fish think they have found a place to shelter from predators, not realising they are swimming into danger. It's not known why this strategy has only recently been identified, but scientists speculate that it's a result of changing environmental conditions -- or that whales are being more closely monitored than ever before by drones and other modern technologies.

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Biochemists have succeeded in resurrecting the ancestral genes of five detoxifying enzymes which are present in all tetrapods to show how their divergence in function has occurred.

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By simulating early Earth conditions in the lab, researchers have found that without specific amino acids, ancient proteins would not have known how to evolve into everything alive on the planet today -- including plants, animals, and humans.

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Textbooks will tell you that in dividing cells, production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level. Molecular biologists have now discovered that this is not true: protein synthesis shows two peaks and lipid synthesis peaks once.

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Haematopoietic stem cell transplantation for the treatment of severe blood cancers is the only medical intervention that has cured two people living with HIV in the past. An international group of physicians and researchers has now identified another case in which HIV infection has been shown to be cured in the same way. The successful healing process of this third patient was for the first time characterized in great detail virologically and immunologically over a time span of ten years.

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Influenza viruses are becoming increasingly resilient to medicines. For this reason, new active ingredients are needed. Important findings in this regard have been provided: for the virus to proliferate, the polymerase of the influenza A virus has to be modified many times through enzymes in the host cells. The team of researchers was able to produce a comprehensive map of types of modification. Medicines directed against the enzymes woud be resilient to rapid mutations in the virus, thus offering great potential for the future.

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Scientists who study the origins and evolution of the plague have examined hundreds of ancient human teeth from Denmark, seeking to address longstanding questions about its arrival, persistence and spread within Scandinavia.

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A team has developed a method for selectively manipulating genetically engineered cells with ultrasound.

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Psyllium fiber protects against ulcerative colitis and suppresses inflammation by activating the bile acid nuclear receptor, a mechanism that was previously unrecognized, according to a new study.

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When scientists disabled a single regulatory gene in a species of sea anemone, a stinging cell that shoots a venomous miniature harpoon for hunting and self-defense shifted to shoot a sticky thread that entangles prey instead, according to a new study.

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A recent excavation in Megiddo, Israel, unearthed the earliest example of a particular type of cranial surgery in the Ancient Near East -- and potentially one of the oldest examples of leprosy in the world.